Quinone and hydroquinone lipids
Medchemexpress LLC Alpha-Vitamin E ((+)-alpha-Tocopherol) | 59-02-9 | 430.71 | 50 G
α-Vitamin E ((+)-α-Tocopherol) is a naturally occurring form of vitamin E and a potent antioxidant.
- Potent antioxidant.
- Peroxyl radical scavenger, maintaining the integrity of long-chain polyunsaturated fatty acids in cell membranes.
- Inhibits PKC in various cell types, leading to inhibition of platelet aggregation, endothelial cell nitric oxide production, and superoxide production in neutrophils and macrophages.
- Exposure induces activation of MAP kinase and PI3 kinase (PI3K) pathways.
- Proposed benefits for influenza virus A infection, with possible activity against hepatitis B and C.
- Prevents increases in pro-inflammatory cytokines IL-1, IL-6, and IFN-γ mRNA and protein in ischemic-reperfused myocardium.
- Ameliorates diabetic nephropathy in mice by activating diacylglycerol kinase α (DGKα) and preventing podocyte loss.
Medchemexpress LLC Resomelagon acetate (AP1189 acetate) | 1809420-72-1 | MFCD00000305 | 99.8% | 358.35 | 5 MG
Resomelagon acetate (AP1189 acetate) is a potent, orally active melanocortin receptor (MR) agonist, specifically targeting MC1 and MC3. It induces ERK1/2 phosphorylation and Ca2+ mobilization, exhibiting anti-inflammatory activity. This compound is applicable for research in obesity and chronic inflammation.
- Potent, orally active melanocortin receptor agonist
- Specifically targets MC1 and MC3
- Induces ERK1/2 phosphorylation and Ca2+ mobilization
- Exhibits anti-inflammatory activity
- Inhibits TNF-α release and efferocytosis
- Promotes resolution of acute inflammation
- Reduces arthritis in mice
Abcam Tiron, supero x ide scavenger and antio x idant, 25G
MW 314.2 Da. Cell permeable superoxide scavenger and antioxidant. Also used as indicator for complexometry. Can form complexes with titanium and iron.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC L-Glutamic acid, polymer with L-alanine, L-lysine and L-tyrosine, acetate (salt) | 147245-92-9 | 98.0% | 25 MG
L-Glutamic acid, polymer with L-alanine, L-lysine and L-tyrosine, acetate (salt) | 147245-92-9 | 98.0% | 25 MG
Medchemexpress LLC 9-Nitroanthracene-d9 1mg
9-Nitroanthracene-d9 is the deuterium labeled 9-Nitroanthracene[1]
Sigma Aldrich Fine Chemicals Biosciences DL-alpha-Tocopherol acetate >=96% (HPLC) | 7695-91-2 | MFCD00072042 | 100G
DL-alpha-Tocopherol acetate >=96% (HPLC) | Purity: >=96% (HPLC) | Mol Wt: 472.74 | 7695-91-2 | MFCD00072042 | 100G
Medchemexpress LLC a-Tocopherol phospha 10mg
-Tocopherol phosphate disodium is an antioxidant that protects against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model -Tocopherol phosphate disodium exhibits angiogenesis-promoting activity[1][2]
Medchemexpress LLC All-trans-retinol | 68-26-8 | 99.3% | 5 MG
Vitamin A (all-trans-Retinol) is an endogenous metabolite. It plays a role in various biological processes and is studied in contexts such as human gut microbiota metabolism, cellular effects on fibroblasts and cancer cell lines, and its metabolism in hepatic microsomes.
- Endogenous metabolite
- Role in human gut microbiota metabolism
- Exhibits cellular effects on fibroblasts and carcinoma cell lines
- Metabolism involves hepatic microsomes
- Studied in relation to high-fat diets and methionine-choline deficient diets
Medchemexpress LLC γ-Tocopherol | 54-28-4 | 1 ML
γ-Tocopherol, also known as D-γ-Tocopherol, is a natural form of Vitamin E found in many plant seeds such as corn oil and soybeans. It functions as a potent cyclooxygenase (COX) inhibitor and exhibits anti-inflammatory and anti-cancer properties. This product is supplied as a colorless to light yellow liquid.
- Potent cyclooxygenase (COX) inhibitor
- Possesses anti-inflammatory properties
- Demonstrates anti-cancer activity
- Well absorbed and accumulates in some human tissues
- Inversely associated with the incidence of cardiovascular disease and prostate cancer
Medchemexpress LLC Betaine-d9 chloride | 285979-85-3 | 162.66 | 5 MG
Betaine-d9 (chloride) is the deuterium labeled Betaine chloride. This compound can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Vitamin K | 12001-79-5 | 98.7% | 5 MG
Vitamin K is known as the blood-clotting vitamin and is vital for the function of numerous proteins, including coagulation factors, osteocalcin, and matrix-Gla protein. It is available as a liquid and is intended for research use only.
- Important for blood clotting and protein function.
- Liquid appearance.
- Stable under recommended storage conditions.
- Harmful if swallowed.
- Causes skin and serious eye irritation.
- May cause respiratory irritation.
- Store in a cool, well-ventilated area away from direct sunlight.
- Recommended storage for pure form: -20°C for 3 years, 4°C for 2 years.
- Recommended storage in solvent: -80°C for 6 months, -20°C for 1 month.
- This product is for research use only and not for human use.
Sigma Aldrich Fine Chemicals Biosciences (+)-alpha-Tocopherol acetate oil or semi-solid, ~1360 IU/g | 58-95-7 | MFCD00072052 | 10G
(+)-alpha-Tocopherol acetate oil or semi-solid, ~1360 IU/g | Mol Wt: 472.74 | 58-95-7 | MFCD00072052 | 10G
Medchemexpress LLC All-trans-retinol | 68-26-8 | MFCD00001552 | 98.3% | 50 MG
Vitamin A (all-trans-Retinol) is an endogenous metabolite for research applications. This solid compound typically appears off-white to yellow and is known for its cytotoxic and growth inhibitory activities against various cell lines, making it suitable for studies in cellular effects and metabolic pathways.
- Endogenous metabolite
- Used for research applications
- Solid form, off-white to yellow color
- Soluble in ethanol (100 mg/mL), requiring ultrasonic aid for dissolution
- Exhibits cytotoxicity against human normal fibroblasts
- Shows growth inhibitory activity against human cancer cell lines
- Unstable in solutions; freshly prepared solutions are recommended